Deletion of STAT3 from Foxd1 Cell Population Protects Mice from Kidney Fibrosis by Inhibiting Pericytes Trans-differentiation and Migration

Signal transduction and activator of transcription 3 (STAT3) activation increased migration and profibrotic signaling in genome-edited, pericyte-like cells. Conversely, blocking Stat3 inhibited detachment, migration, and profibrotic signaling.