CircRBM33 Downregulation Inhibits Hypoxia-Induced Glycolysis and Promotes Apoptosis of Breast Cancer Cells via a MicroRNA-542-3p/HIF-1α Axis

Breast cancer clinical tissue samples were collected to test differential expressions of circRBM33, miR-542-3p, and HIF-1α. MCF-7 cells were subjected to normoxia or hypoxia and transfected with plasmids that regulated CircRBM33, miR-542-3p, and HIF-1α expression levels.