Superoxide Anion Radical Induced Phototoxicity of 2,4, 5,6-Tetraminopyrimidine Sulfate via Mitochondrial-Mediated Apoptosis in Human Skin Keratinocytes at Ambient UVR Exposure

Researchers studied the photosensitization potential and mechanism involved in dermal phototoxicity of 2,4,5,6-tetraaminopyrimidine sulfate exposed to the dark and UVA/UVB/Sunlight by using different in-chemico and mammalian HaCaT cells, as test systems.