Targeted Cell Therapy for Partial-Thickness Cartilage Defects Using Membrane Modified Mesenchymal Stem Cells by Transglutaminase 2

By modifying a functional polypeptide on the mesenchymal stem cell plasma membrane and exploiting the high expression of transglutaminase 2 in the regions of injured cartilage, researchers achieved targeted recognition and capture of modified MSCs by injured articular chondrocytes