By modifying a functional polypeptide on the mesenchymal stem cell plasma membrane and exploiting the high expression of transglutaminase 2 in the regions of injured cartilage, researchers achieved targeted recognition and capture of modified MSCs by injured articular chondrocytes
[Biomaterials]
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Li, H., Jin, Y., Zhao, Y., Li, W., He, Z., Zhang, Q., Huang, H., Lin, J., Chen, Y., Xing, D., Du, Y., & Lin, J. (2021). Targeted cell therapy for partial-thickness cartilage defects using membrane modified mesenchymal stem cells by transglutaminase 2. Biomaterials, 275, 120994. https://doi.org/10.1016/j.biomaterials.2021.120994 Cite