USP33 Deubiquitinates and Stabilizes HIF-2alpha to Promote Hypoxia Response in Glioma Stem Cells

By
Justin.choi
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0
85
Researchers identified USP33 as essential deubiquitinase that stabilized HIF-2alpha protein in an ERK1/2-dependent manner to promote hypoxia response in cancer cells.
[EMBO Journal]

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AbstractGraphical Abstract