One major challenge is determining the cancer stem cell properties that can be exploited as therapeutic targets. Another challenge is identifying suitable breast cancer stem cells (BCSC) biomarkers to assess the efficacy of novel BCSC-targeted therapies.
[Pharmacological Research]
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Zeng, X., Liu, C., Yao, J., Wan, H., Wan, G., Li, Y., & Chen, N. (2021). Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications. Pharmacological Research, 163, 105320. https://doi.org/10.1016/j.phrs.2020.105320 Cite