Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell NewsInvestigators summarized the novel regulators existed in breast cancer stem cells (BCSCs) and their niches for BCSC heterogeneity which has been discovered in recent years, and discuss their regulation mechanisms and the latest corresponding cancer treatments.
[Seminars in Cancer Biology]
6445212 4IAZD3VV items 1 apa 0 default asc 1 160458 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-995555a615d96bfc5a6cf6394b43f1a1%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%224IAZD3VV%22%2C%22library%22%3A%7B%22id%22%3A6445212%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Zhang%20et%20al.%22%2C%22parsedDate%22%3A%222021-03-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EZhang%2C%20R.%2C%20Tu%2C%20J.%2C%20%26amp%3B%20Liu%2C%20S.%20%282021%29.%20Novel%20molecular%20regulators%20of%20breast%20cancer%20stem%20cell%20plasticity%20and%20heterogeneity.%20%3Ci%3ESeminars%20in%20Cancer%20Biology%3C%5C%2Fi%3E.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.semcancer.2021.03.008%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.semcancer.2021.03.008%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6445212%26amp%3Bitem_key%3D4IAZD3VV%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Novel%20molecular%20regulators%20of%20breast%20cancer%20stem%20cell%20plasticity%20and%20heterogeneity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rui%22%2C%22lastName%22%3A%22Zhang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juchuanli%22%2C%22lastName%22%3A%22Tu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Suling%22%2C%22lastName%22%3A%22Liu%22%7D%5D%2C%22abstractNote%22%3A%22Tumors%20consist%20of%20heterogeneous%20cell%20populations%2C%20and%20tumor%20heterogeneity%20plays%20key%20roles%20in%20regulating%20tumorigenesis%2C%20metastasis%2C%20recurrence%20and%20resistance%20to%20anti-tumor%20therapies.%20More%20and%20more%20studies%20suggest%20that%20cancer%20stem%20cells%20%28CSCs%29%20promote%20tumorigenesis%2C%20metastasis%2C%20recurrence%20and%20drug%20resistance%20as%20well%20as%20are%20the%20major%20source%20for%20heterogeneity%20of%20cancer%20cells.%20CD24%5Cu2212CD44%2B%20and%20ALDH%2B%20are%20the%20most%20common%20markers%20for%20breast%20cancer%20stem%20cells%20%28BCSCs%29.%20Previous%20studies%20showed%20that%20different%20BCSC%20markers%20label%20different%20BCSC%20populations%2C%20indicating%20the%20heterogeneity%20of%20BCSCs.%20Therefore%2C%20defining%20the%20regulation%20mechanisms%20of%20heterogeneous%20BCSCs%20is%20essential%20for%20precisely%20targeting%20BCSCs%20and%20treating%20breast%20cancer.%20In%20this%20review%2C%20we%20summarized%20the%20novel%20regulators%20existed%20in%20BCSCs%20and%20their%20niches%20for%20BCSC%20heterogeneity%20which%20has%20been%20discovered%20in%20recent%20years%2C%20and%20discussed%20their%20regulation%20mechanisms%20and%20the%20latest%20corresponding%20cancer%20treatments%2C%20which%20will%20extend%20our%20understanding%20on%20BCSC%20heterogeneity%20and%20plasticity%2C%20and%20provide%20better%20prognosis%20prediction%20and%20more%20efficient%20novel%20therapeutic%20strategies%20for%20breast%20cancer.%22%2C%22date%22%3A%22March%2015%2C%202021%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.semcancer.2021.03.008%22%2C%22ISSN%22%3A%221044-579X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS1044579X21000584%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-03-24T16%3A56%3A50Z%22%7D%7D%5D%7D
Zhang, R., Tu, J., & Liu, S. (2021). Novel molecular regulators of breast cancer stem cell plasticity and heterogeneity. Seminars in Cancer Biology. https://doi.org/10.1016/j.semcancer.2021.03.008 Cite
