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Pulmonary Cell NewsInvestigators interrogated gene expression in separate microenvironments of glioblastoma organoid models that mimicked the transition between nutrient-rich and nutrient-poor pseudopalisading/perinecrotic tumor zones using spatial-capture RNA-sequencing.
[Acta Neuropathologica Communications]
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Shakya, S., Gromovsky, A. D., Hale, J. S., Knudsen, A. M., Prager, B., Wallace, L. C., Penalva, L. O. F., Brown, H. A., Kristensen, B. W., Rich, J. N., Lathia, J. D., Brown, J. M., & Hubert, C. G. (2021). Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches. Acta Neuropathologica Communications, 9(1), 101. https://doi.org/10.1186/s40478-021-01205-7 Cite
