NewslettersCancer Stem Cell NewsHematopoiesis NewsTargeting miR-126 in inv(16) Acute Myeloid Leukemia Inhibits Leukemia Development and Leukemia Stem Cell MaintenanceBy Justin.choi - October 22, 20210255The authors showed that miR-126 enhanced MYC activity through the SPRED1/PLK2-ERK-MYC axis. Genetic deletion of miR-126 significantly reduced acute myeloid leukemia rate and extended survival in CBFB-MYH11 knock-in mice.[Nature Communications] 6445212 AAAAAAAA items 1 apa 0 default asc 1 168101 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/Full Article