Pharmacological Inhibition of p38 MAPK Rejuvenates Bone Marrow Derived-Mesenchymal Stromal Cells and Boosts their Hematopoietic Stem Cell-Supportive Ability

Researchers found that the ex vivo expanded mesenchymal stem cells showed activated p38 mitogen-activated protein kinase p38 (MAPK) signaling and exhibited increased oxidative stress.