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Pulmonary Cell NewsIn constitutive GPR182-deficient mice, as well as after induced endothelium-specific loss of GPR182, investigators found significant increases in the plasma levels of CXCL10, CXCL12, and CXCL13.
[Proceedings of the National Academy of Sciences of the United States of America]
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Mercier, A. L., Bonnavion, R., Yu, W., Alnouri, M. W., Ramas, S., Zhang, Y., Jäger, Y., Roquid, K. A., Jeong, H.-W., Sivaraj, K. K., Cho, H., Chen, X., Strilic, B., Sijmonsma, T., Adams, R., Schroeder, T., Rieger, M. A., & Offermanns, S. (2021). GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. Proceedings of the National Academy of Sciences, 118(17). https://doi.org/10.1073/pnas.2021596118 Cite
