SPNS2 Enables T Cell Egress from Lymph Nodes during an Immune Response

By
Justin.choi
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Using a model of dermal inflammation, investigators demonstrated that SPNS2 supplies the S1P that guided T cells out of lymph nodes with an ongoing immune response.
[Cell Reports]
Okuniewska, M., Fang, V., Baeyens, A., Raghavan, V., Lee, J.-Y., Littman, D. R., & Schwab, S. R. (2021). SPNS2 enables T cell egress from lymph nodes during an immune response. Cell Reports, 36(2). https://doi.org/10.1016/j.celrep.2021.109368 Cite
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