Human ESC-Derived Neuromesodermal Progenitors (NMPs) Successfully Differentiate into Mesenchymal Stem Cells (MSCs)

The authors generated NMPs from human ESCs, subsequently derived MSCs and characterized this cell population in vitro and in vivo. NMP-derived MSCs were plastic adherent fibroblast like cells with colony forming capacity and trilineage (osteo-, chondro- and adipo-genic) differentiation potential.