Human Umbilical Cord Mesenchymal Stem Cells Deliver Exogenous miR-26a-5p via Exosomes to Inhibit Nucleus Pulposus Cell Pyroptosis through METTL14/NLRP3

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Justin.choi
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The human umbilical cord MSC exosomes were found to effectively improve the viability of nucleus pulposus cells and protect them from pyroptosis through targeting METTL14, with a methyltransferase catalyzing m6A modification.
[Molecular Medicine]
Yuan, X., Li, T., Shi, L., Miao, J., Guo, Y., & Chen, Y. (2021). Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3. Molecular Medicine, 27(1), 91. https://doi.org/10.1186/s10020-021-00355-7 Cite
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