B cells

[Science Immunology] Investigators found that monophosphoryl lipid A (MPLA) self-assembled with saponins to form particles physically resembling immune-stimulatory complexes, which they termed saponin/MPLA nanoparticles.

[Science Advances] The authors examined how during the course of B cell activation E2A and E2-2 gene expression was regulated.

[Immunity] The composition of the intestinal microbiota is associated with both the development of tumors and the efficacy of anti-tumor immunity. Researchers examined the impact of microbiota-specific T cells in anti-colorectal cancer immunity.

[Science Advances] To probe the role of B cells in biomaterial scaffold response, scientists evaluated the B cell response to biomaterial materials implanted in a muscle wound using a biological ECM as a reference for a naturally derived material, and synthetic polyester polycaprolactone as a reference for a synthetic material.

[Human Immunology] The authors reviewed the molecular mechanisms and the role of immune cells and responses involved in pulmonary hypertension development.

[Cell Reports] To gain a deeper understanding of the molecular characteristics associated with CAR T cell differentiation, researchers performed longitudinal genome-wide DNA methylation profiling of CD8+ CD19-CAR T cells post-infusion in acute lymphoblastic leukemia patients.