A Particulate Saponin/TLR Agonist Vaccine Adjuvant Alters Lymph Flow and Modulates Adaptive Immunity

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Investigators found that monophosphoryl lipid A (MPLA) self-assembled with saponins to form particles physically resembling immune-stimulatory complexes, which they termed saponin/MPLA nanoparticles.
[Science Immunology]

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Abstract