Nestin

[Scientific Reports] Proteomic analyses of human angiogenesis-related factors produced by human adipose tissue-derived stromal/stem cells (hADSCs) showed that both pro- and anti-angiogenic factors were produced by hADSCs in vitro, but only those related to vessel maturation were detectable in vivo.

[Scientific Reports] Researchers identified brain specific expression of a novel C3G isoform in mice and humans. This isoform has an insert in the Crk-binding region, generating a polypeptide of 175 kDa, unlike the previously known 140 kDa form expressed in all other tissues.

[Frontiers in Cell and Developmental Biology] The authors report a protocol that efficiently induced near synchronous rosette organization, even from human PSC-derived neural progenitor cell monolayers that do not generally exhibit rosette formation using previously existing protocols.

[Cell Metabolism] Investigators studied the contribution of nestin+ bone marrow mesenchymal stem cells to MLL-AF9-driven acute myeloid leukemia development and chemoresistance in vivo.

[Cell Metabolism] The authors studied the contribution of nestin+ bone marrow mesenchymal stem cells to MLL-AF9-driven acute myeloid leukemia development and chemoresistance in vivo.

[Scientific Reports] Scientists studied the importance of paracrine signaling in the glioma microenvironment by focusing on the celecoxib-mediated role of chemokines C–C motif ligand 2, C-X-C ligand 10, and their receptors, CCR2 and CXCR3, in glioma stem cells (GSCs) and a GSC-bearing malignant glioma model.