leukocytes

[International Journal of Oncology] Researchers examined the competing endogenous RNA network in cutaneous squamous cell carcinoma.

[Clinical Cancer Research] Patient tumor organoids (PTO) were fabricated using unsorted tumor cells with and without enrichment with patient matched immune components derived from peripheral blood leukocytes, spleen, or lymph nodes.

[Oncogene] Scientists summarized recent findings on the heterogeneous subset composition of B cells in both human and mouse tumor models and their different impacts on disease progression.

[Nature Medicine] Investigators studied a patient with inherited PD-1 deficiency and tuberculosis who died of pulmonary autoimmunity. The patient’s leukocytes did not express PD-1 or respond to PD-1-mediated suppression.

[Scientific Reports] In wild-type (WT) muscle, investigators observed an upregulation of PN-1 mRNA and protein after ischemia. Angiography analysis showed that femoral artery perfusion was more rapidly restored in PN-1−/− mice than in WT mice.

[Journal of Pathology] Using single cell RNA-sequencing, investigators identified and validated the in situ localization of three smooth muscle subtypes and two novel fibroblast subtypes in human prostate.