macrophages

[Nature Communications] The authors reported that in chow-fed, reproductively senescent female mice but not in age-matched male mice, deficiency in the thiol transferase glutaredoxin 1 promoted dysregulated macrophage phenotypes as well as rapid weight gain and atherogenesis.

[Arteriosclerosis Thrombosis and Vascular Biology] Scientists discuss key findings from the latest research that give insight into the mechanisms by which clonal expansion of vascular cells contributes to disease pathology.

[Nature Communications] Scientists demonstrated that yeast-derived particulate β-glucan, an inducer of trained immunity, trafficed to the pancreas, which caused a CCR2-dependent influx of monocytes/macrophages to the pancreas that display features of trained immunity.

[PLoS Pathogens] Similar to other filoviruses, recombinant Lloviu virus formed filamentous virions and induced the formation of characteristic inclusions in the cytoplasm of the infected cells, as shown by electron microscopy.

[Blood] The authors showed that late-stage Non-Hodgkin's Lymphoma was resistant to therapy targeting phagocytosis checkpoint CD47, due to the compromised capacity of tumor-associated macrophages to phagocytose lymphoma cells.

[Phytotherapy Research] Scientists investigated the underlying mechanism and pharmacological effect of rhamnazin against pulmonary disorders.