Tag results:
macrophages
Immune Regulation News
Long-Term Recruitment of Endogenous M2 Macrophages by Platelet Lysate-Rich Plasma Macroporous Hydrogel Scaffold for Articular Cartilage Defect Repair
[Advanced Healthcare Materials] A platelet lysate-rich plasma macroporous hydrogel scaffold with around 100 μm pore size and 1.25 MPa Young's modulus was developed to sustainedly recruit and polarize endogenous anti-inflammatory macrophages for improving cartilage defect repair.
Immune Regulation News
M-CSFR/CSF1R Signaling Regulates Myeloid Fates in Zebrafish via Distinct Action of Its Receptors and Ligands
[Blood Advances] The authors investigated the roles of zebrafish colony-stimulating factor receptor (Csf1rs) and their ligands - Csf1a, Csf1b and Il34, in embryonic and adult myelopoiesis.
Endothelial Cell News
miR-125a-5p Attenuates Macrophage-Mediated Vascular Dysfunction by Targeting Ninjurin1
[Cell Death & Differentiation] Researchers investigated the role of Ninj1 in physiological and pathological conditions and developed a strategy to regulate Ninj1 using specific miRNAs under pathological conditions.
Extracellular Matrix News
Enhanced Tendon Healing by a Tough Hydrogel with an Adhesive Side and High Drug-Loading Capacity
[Nature Biomedical Engineering] Investigators reported that a hydrogel serving as a high-capacity drug depot and combining a dissipative tough matrix on one side and a chitosan adhesive surface on the other side supported tendon gliding and strong adhesion to tendon on opposite surfaces of the hydrogel.
Cell Therapy News
Systemic and Local Innate Immune Responses to Surgical Co-Transplantation of Mesenchymal Stromal Cells and Biphasic Calcium Phosphate for Bone Regeneration
[Acta Biomaterialia] Scientists assessed the local and systemic innate immune responses to implantation of biphasic calcium phosphate biomaterial alone, or with bone marrow derived MSC, in critical-sized calvarial bone defects of Lewis rats.
Human Immunology News
TMT-Based Quantitative Proteomic Profiling of Human Monocyte-Derived Macrophages and Foam Cells
[Proteome Science] Human peripheral blood mononuclear cells were stimulated with macrophage colony-stimulating factor, and obtained macrophages were transformed into foam cells by oxidized low-density lipoprotein.