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neutrophils

Resident Macrophage-Dependent Immune Cell Scaffolds Drive Anti-Bacterial Defense in the Peritoneal Cavity

[Immunity] Scientists examined the mechanisms that control bacterial infection in the peritoneum using a mouse model of abdominal sepsis following intraperitoneal Escherichia coli infection.

The Role of Streptococcal Cell-Envelope Proteases in Bacterial Evasion of the Innate Immune System

[Journal of innate Immunity] Scientists focused on a family of S8 subtilisin-like serine proteases expressed as cell-envelope proteases (CEPs) by group A and group B streptococci.

Lung Mesenchymal Stromal Cells Influenced by Th2 Cytokines Mobilize Neutrophils and Facilitate Metastasis by Producing Complement C3

[Nature Communications] The authors found that lung mesenchymal stromal cells at pre-metastatic stage possess potent metastasis-promoting activity.

Perturbed NK Cell Homeostasis Associated with Disease Severity in Chronic Neutropenia

[Blood] Scientists used high-resolution flow- and mass cytometry to examine NK cell repertoires in 64 patients with neutropenia and 27 healthy age- and gender-matched donors.

Heightened Turnover and Failed Maturation of Monocyte-Derived Macrophages in Murine Chronic Granulomatous Disease

[Blood] The authors assessed the effects of Nox2 absence on monocyte-derived macrophages in gp91phox-/y mice during zymosan-induced peritonitis.

Lung Mesenchymal Stromal Cells Influenced by Th2 Cytokines Mobilize Neutrophils and Facilitate Metastasis by Producing Complement C3

[Nature Communications] Pre-metastatic niche formation is critical for the colonization of disseminated cancer cells in distant organs. Researchers found that lung mesenchymal stromal cells at pre-metastatic stage possess potent metastasis-promoting activity.

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