Tag results:

p21

Knockdown of the Prognostic Cancer Stem Cell Marker Musashi-1 Decreases Radio-Resistance While Enhancing Apoptosis in Hormone Receptor-Positive Breast Cancer Cells via p21WAF1/CIP1

[Journal of Cancer Research and Clinical Oncology] Musashi-1 was artificially downregulated in MCF-7 breast cancer cells and implications for cancer stem cell markers, cell apoptosis and apoptosis regulator p21, proliferation and radiation response were analyzed via flow cytometry and colony formation.

Effect of the Phenylpyrrole Fungicide Fludioxonil on Cell Proliferation and Cardiac Differentiation in Mouse Embryonic Stem Cells

[Reproductive Toxicology] The potential effect of fludioxonil on cardiac differentiation was evaluated in mouse ESCs. Exposure to fludioxonil resulted in reduced size of mouse embryoid bodies and induced increasing expression levels of the pluripotency markers Oct4, Sox2 and Nanog.

ZFP36 Protects Lungs from Intestinal I/R-Induced Injury and Fibrosis through the CREBBP/p53/p21/Bax Pathway

[Cell Death & Disease] Researchers investigated the involvement of zinc finger protein 36 (ZFP36) and cAMP‐response element-binding protein binding protein (CREBBP) on ischemia–reperfusion (I/R)-induced lung injury in vivo and in vitro.

Reversal of Senescence-Associated Beta-Galactosidase Expression during In Vitro Three-Dimensional Tissue-Engineering of Human Chondrocytes in a Polymer Scaffold

[Scientific Reports] Researchers evaluated a three-dimensional thermo-reversible gelation polymer matrix environment for its capabilities to reverse cellular senescence.

Th17/IL-17 Induces Endothelial Cell Senescence via Activation of NF-κB/p53/RB Signaling Pathway

[Laboratory Investigation] The proportion of Th17 cells in the spleen and the expression levels of IL-17A, IL-6, and vascular cell adhesion molecule- in mice of different ages were increased with aging.

Inverse and Reciprocal Regulation of p53/p21 and BMI-1 Modulates Vasculogenic Differentiation of Dental Pulp Stem Cells

[Cell Death & Disease] Dental pulp stem cells seeded in biodegradable scaffolds and transplanted into immunodeficient mice generated mature human blood vessels invested with smooth muscle actin-positive mural cells.

Popular