Effect of the Phenylpyrrole Fungicide Fludioxonil on Cell Proliferation and Cardiac Differentiation in Mouse Embryonic Stem Cells

The potential effect of fludioxonil on cardiac differentiation was evaluated in mouse ESCs. Exposure to fludioxonil resulted in reduced size of mouse embryoid bodies and induced increasing expression levels of the pluripotency markers Oct4, Sox2 and Nanog.