pulmonary cells

[Cell Discovery] Comparison of the transcriptomes of the bronchoalveolar microenvironment and peripheral blood indicates alveolar macrophages, alveolar epithelial cells, and monocytes in lungs as the potential main sources of elevated cytokines mediating systemic immune responses and organ damages.

[Cell Death Discovery] When combined with dabrafenib and/or trametinib, Melaleuca alternifolia synergistically reduced the viability of melanoma cells by activating apoptosis.

[Experimental and Molecular Medicine] Scientists evaluated the effect of neutrophil elastase on lipopolysaccharide - induced interleukin 8 production and determined the molecular mechanism in human bronchial epithelial cells.

[Cell Death & Disease] ALKBH5 gain- or loss-of function could effectively reverse LKB1 regulated cell proliferation, colony formation, and migration of KRAS-mutated lung cancer cells.

[iScience] Investigators showed that KEAP1 deficiency promotes glucose dependency in lung cancer cells, and KEAP1-mutant/deficient lung cancer cells were more vulnerable to glucose deprivation than their WT counterparts.

[Nature Communications] Scientists developed a strategy that enabled single-cell lipidomic analysis with high structural specificity and classified four subtypes of human breast cancer cells.