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Pulmonary Cell NewsComparison of the transcriptomes of the bronchoalveolar microenvironment and peripheral blood indicates alveolar macrophages, alveolar epithelial cells, and monocytes in lungs as the potential main sources of elevated cytokines mediating systemic immune responses and organ damages.
[Cell Discovery]
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Tan, Y., Zhang, W., Zhu, Z., Qiao, N., Ling, Y., Guo, M., Yin, T., Fang, H., Xu, X., Lu, G., Zhang, P., Yang, S., Fu, Z., Liang, D., Xie, Y., Zhang, R., Jiang, L., Yu, S., Lu, J., … Chen, S. (2021). Integrating longitudinal clinical laboratory tests with targeted proteomic and transcriptomic analyses reveal the landscape of host responses in COVID-19. Cell Discovery, 7(1), 1–19. https://doi.org/10.1038/s41421-021-00274-1 Cite
