TNF-α

[Amb Express] Administration of polysaccharide Pleurotus ostreatus showed a significant decrease in tumor cell metastasis while the increase in the survival period among mice models of H22 malignant ascites.

[iScience] Investigators utilized the biotin ligase -TurboID fusion with Toxoplasma gondii surface antigen 1 (TgSAG1) to identify the host proteins interacting with TgSAG1, and identified that S100A6 was co-localized with TgSAG1 when T. gondii attached to the host cell.

[Pharmacological Research] Melittin (MEL)-diclofenac (DCL) nano-complexes exhibited better regenerated epithelium, keratinization, epidermal proliferation, and granulation tissue formation and better wound healing activity than controls. Treatment of wounded skin with MEL-DCL nano-complexes showed an increase in mRNA expression levels of collagen.

[Cellular & Molecular Immunology] The presence of the p40-EBI3 heterodimer was confirmed by ELISA, immunoprecipitation, and western blotting. A p40-EBI3 vector and p40-EBI3-Fc protein were synthesized to confirm the immunological role of this protein in mice with collagen-induced arthritis

[Laboratory Investigation] Researchers demonstrated that lipopolysaccharide promoted c-Jun N-terminal kinase signaling pathway activation and endogenous tumor necrosis factor-α secretion in pulmonary macrophages.

[Scientific Reports] Scientists utilized cromolyn, a mast cell inhibitor with anti-inflammatory capabilities, and its fluorinated analogue F-cromolyn to study fibrosis-related protein regulation and secretion downstream of neuroinflammation and their ability to promote microglial phagocytosis and neurite outgrowth.