Review

[Cancer And Metastasis Reviews] CSCs maintain the cancer cell plasticity, EMT, and epigenetic plasticity. EMT contributes to increased cell migration and greater diversity within tumors, while epigenetic changes, stem cell factors, and various signaling pathways allow cancer cells to maintain various phenotypes, giving rise to intra- and inter-tumoral heterogeneity.

[Gynecologic And Obstetric Investigation] The authors summarize surgical interventions in the treatment of Gestational Trophoblastic Disease and Gestational Trophoblastic Neoplasia. Investigators reviewed indications, efficacy, possible complications and oncological outcomes of surgery.

[Journal Of Controlled Release] The authors give an overview of the potential applications of electrospun fibers in skin therapy. In addition to the treatment of bacterial, diabetic and burn wounds, focus is placed on inflammatory diseases such as atopic dermatitis and psoriasis.

[Immunity] The authors argue for the notion of immunotherapies as “pro-drugs” that act to augment or modulate T cells, which ultimately serve as the drug in vivo, and for the importance of overall immune health in cancer treatment and prevention.

[Trends In Pharmacological Sciences] The authors summarize our current understanding of Celiac disease pathogenesis and how it is being harnessed for therapeutic design and development.

[Nature Reviews Immunology] Scientists explore the complex circuitries that link stress to perturbations in the cancer-immune dialogue and their implications for therapeutic approaches to cancer.