Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell NewsThe authors investigated the transport and uptake of liposomes composed of docosahexaenoic acid‐enriched phosphatidylcholine, phosphatidylserine, and sulfoquinovosyl diacylglycerol derived from marine products on multilamellar vesicles in small intestinal epithelial cell models.
[Lipids]
1254621 {1254621:TGKATSAJ} apa 50 1 152966 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-53d745c51925f60108c0ae1ec5f21c72%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22TGKATSAJ%22%2C%22library%22%3A%7B%22id%22%3A1254621%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Konishi%20et%20al.%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKonishi%2C%20K.%2C%20Du%2C%20L.%2C%20Francius%2C%20G.%2C%20Linder%2C%20M.%2C%20Sugawara%2C%20T.%2C%20Kurihara%2C%20H.%2C%20%26amp%3B%20Takahashi%2C%20K.%20%28n.d.%29.%20Lipid%20Composition%20of%20Liposomal%20Membrane%20Largely%20Affects%20Its%20Transport%20and%20Uptake%20through%20Small%20Intestinal%20Epithelial%20Cell%20Models.%20%3Ci%3ELipids%3C%5C%2Fi%3E%2C%20%3Ci%3En%5C%2Fa%3C%5C%2Fi%3E%28n%5C%2Fa%29.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Flipd.12269%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Flipd.12269%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D1254621%26amp%3Bitem_key%3DTGKATSAJ%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Lipid%20Composition%20of%20Liposomal%20Membrane%20Largely%20Affects%20Its%20Transport%20and%20Uptake%20through%20Small%20Intestinal%20Epithelial%20Cell%20Models%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Keisuke%22%2C%22lastName%22%3A%22Konishi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lei%22%2C%22lastName%22%3A%22Du%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gr%5Cu00e9gory%22%2C%22lastName%22%3A%22Francius%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michel%22%2C%22lastName%22%3A%22Linder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tomoaki%22%2C%22lastName%22%3A%22Sugawara%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hideyuki%22%2C%22lastName%22%3A%22Kurihara%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Koretaro%22%2C%22lastName%22%3A%22Takahashi%22%7D%5D%2C%22abstractNote%22%3A%22Lipid%20composition%20of%20liposomal%20bilayer%20should%20alter%20the%20cell%20response%20for%20permeability%2C%20transport%2C%20and%20uptake%20in%20small%20intestine.%20This%20work%20was%20done%20to%20investigate%20the%20transport%20and%20uptake%20of%20liposomes%20composed%20of%20docosahexaenoic%20acid-enriched%20phosphatidylcholine%20%28PtdCho%29%2C%20phosphatidylserine%20%28PtdSer%29%2C%20and%20sulfoquinovosyl%20diacylglycerol%20%28SQDG%29%20derived%20from%20marine%20products%20on%20multilamellar%20vesicles%20%28MLV%29%20in%20small%20intestinal%20epithelial%20cell%20models.%20The%20results%20showed%20that%20addition%20of%20PtdSer%20and%20SQDG%20as%20liposomal%20bilayer%20could%20improve%20the%20efficiency%20entrapment%20of%20liposomes.%20The%20liposomes%20containing%20PtdSer%20showed%20higher%20transport%20and%20uptake%20through%20both%20Caco-2%20cell%20and%20M%20cell%20monolayers%20as%20compared%20to%20PtdCho-MLV.%20SQDG-containing%20liposomes%20exhibited%20only%20higher%20transport%20through%20M%20cell%20monolayer%2C%20while%20its%20uptake%20effect%20was%20higher%20both%20in%20Caco-2%20cell%20and%20M%20cell%20monolayers.%20The%20results%20of%20experiments%20done%20with%20endocytosis%20inhibitors%20indicated%20that%20PtdCho-MLV%20must%20be%20transported%20via%20macropinocytosis%20and%20uptaken%20by%20phagocytosis%20in%20M%20cell%20monolayer%20model.%20PtdCho%5C%2FPtdSer-MLV%20and%20PtdCho%5C%2FSQDG-MLV%20might%20be%20transported%20and%20uptaken%20through%20M%20cell%20monolayer%20by%20phagocytosis.%20The%20result%20also%20indicated%20that%20PtdCho%5C%2FSQDG-MLV%20could%20open%20the%20tight%20junction%20of%20small%20intestinal%20epithelial%20cell%20monolayers.%20Furthermore%2C%20our%20findings%20demonstrated%20that%20the%20surface%20status%20of%20cholesterol-containing%20liposomes%20were%20smooth%2C%20but%20they%20did%20not%20affect%20their%20transport%20and%20uptake%20through%20Caco-2%20cell%20and%20M%20cell%20monolayers.%22%2C%22date%22%3A%22%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Flipd.12269%22%2C%22ISSN%22%3A%221558-9307%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Faocs.onlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Flipd.12269%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222020-08-14T19%3A10%3A09Z%22%7D%7D%5D%7D
Konishi, K., Du, L., Francius, G., Linder, M., Sugawara, T., Kurihara, H., & Takahashi, K. (n.d.). Lipid Composition of Liposomal Membrane Largely Affects Its Transport and Uptake through Small Intestinal Epithelial Cell Models. Lipids, n/a(n/a). https://doi.org/10.1002/lipd.12269 Cite
