In Vivo CD8+ T Cell CRISPR Screening Reveals Control by Fli1 in Infection and Cancer

By
Justin.choi
-
0
10
Scientists developed an in vivo T cell CRISPR screening platform and identified a key mechanism restraining T EFF biology through the ETS family TF, Fli1.
[Cell]
Chen, Z., Arai, E., Khan, O., Zhang, Z., Ngiow, S. F., He, Y., Huang, H., Manne, S., Cao, Z., Baxter, A. E., Cai, Z., Freilich, E., Ali, M. A., Giles, J. R., Wu, J. E., Greenplate, A. R., Hakeem, M. A., Chen, Q., Kurachi, M., … Shi, J. (2021). In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer. Cell, 0(0). https://doi.org/10.1016/j.cell.2021.02.019 Cite
AbstractGraphical Abstract