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Pulmonary Cell NewsMechanistically, plectin deficiency in intestinal epithelial cell led to aberrant keratin filament network organization and the formation of dysfunctional hemidesmosomes and intercellular junctions.
[Mucosal Immunology]
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Krausova, A., Buresova, P., Sarnova, L., Oyman-Eyrilmez, G., Skarda, J., Wohl, P., Bajer, L., Sticova, E., Bartonova, L., Pacha, J., Koubkova, G., Prochazka, J., Spörrer, M., Dürrbeck, C., Stehlikova, Z., Vit, M., Ziolkowska, N., Sedlacek, R., Jirak, D., … Gregor, M. (2021). Plectin ensures intestinal epithelial integrity and protects colon against colitis. Mucosal Immunology, 1–12. https://doi.org/10.1038/s41385-021-00380-z Cite
