BMP4 Overexpression Induces the Upregulation of APP/Tau and Memory Deficits in Alzheimer’s Disease

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Justin.choi
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In multiple cell lines, the overexpression of BMP4 increased the expression of Alzheimer’s disease-related proteins, whereas the downregulation of BMP4 demonstrated opposing effects.
[Cell Death Discovery]
Zhang, X., Li, J., Ma, L., Xu, H., Cao, Y., Liang, W., Ma, J., Wang, Z. P., & Li, Y. (2021). BMP4 overexpression induces the upregulation of APP/Tau and memory deficits in Alzheimer’s disease. Cell Death Discovery, 7(1), 1–13. https://doi.org/10.1038/s41420-021-00435-x Cite
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