Researchers found that type 2 immune signaling, mediated via stat6, was absolutely required for epithelialization and granuloma formation.
[Cell]
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Cronan, M. R., Hughes, E. J., Brewer, W. J., Viswanathan, G., Hunt, E. G., Singh, B., Mehra, S., Oehlers, S. H., Gregory, S. G., Kaushal, D., & Tobin, D. M. (2021). A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization. Cell, 0(0). https://doi.org/10.1016/j.cell.2021.02.046 Cite