Macroautophagy/autophagy plays a critical role in spiral ganglion neurons (SGNs) development, but the effect of autophagy on cisplatin-induced SGN injury is unclear. Scientists found that autophagic flux was activated in SGNs after cisplatin damage.
[Autophagy]
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Liu, W., Xu, L., Wang, X., Zhang, D., Sun, G., Wang, M., Wang, M., Han, Y., Chai, R., & Wang, H. (2021). PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage. Autophagy, 0(ja), null. https://doi.org/10.1080/15548627.2021.1905466 Cite