CRISPR-Cas9 and shRNA were used to eliminate TFAP2A expression in HCT116 and a panel of colon cancer cell lines.
[Molecular Cancer Research]
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Beck, A. C., Cho, E., White, J. R., Paemka, L., Li, T., Gu, V. W., Thompson, D. T., Koch, K. E., Franke, C., Gosse, M., Wu, V. T., Landers, S. R., Pamatmat, A. J., Kulak, M. V., & Weigel, R. J. (2021). AP-2alpha Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer. Molecular Cancer Research. https://doi.org/10.1158/1541-7786.MCR-20-0867 Cite