Ubiquitin Specific Peptidase Usp53 Regulates Osteoblast versus Adipocyte Lineage Commitment

Using ChIP-Seq against NACA in parallel with RNA-sequencing, investigators report the identification of Ubiquitin Specific Peptidase 53 (Usp53) as a target gene of parathyroid hormone-activated nascent polypeptide associated complex and coregulator alpha in osteoblasts.