Scrt1 expression was controlled by the transcriptional repressor RE-1 silencing transcription factor (REST) and was increased in an in vitro reprogramming system of pancreatic exocrine cells to β-like cells.
[Scientific Reports]
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Sobel, J., Guay, C., Elhanani, O., Rodriguez-Trejo, A., Stoll, L., Menoud, V., Jacovetti, C., Walker, M. D., & Regazzi, R. (2021). Scrt1, a transcriptional regulator of β-cell proliferation identified by differential chromatin accessibility during islet maturation. Scientific Reports, 11(1), 8800. https://doi.org/10.1038/s41598-021-88003-2 Cite