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Pulmonary Cell NewsResearchers reported CD109/STAT3 axis as crucial for the maintenance of stemness and tumorigenicity of glioma stem cells and as a mediator of chemoresistance.
[JCI Insight]
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Filppu, P., Ramanathan, J. T., Granberg, K. J., Gucciardo, E., Haapasalo, H., Lehti, K., Nykter, M., Joncour, V. L., & Laakkonen, P. (2021). CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity. JCI Insight, 6(9). https://doi.org/10.1172/jci.insight.141486 Cite
