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Pulmonary Cell NewsScientists found increased COUP-TFII expression in myofibroblasts in human fibrotic kidneys, lungs, kidney organoids, and mouse kidneys after injury.
[EMBO Reports]
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Li, L., Galichon, P., Xiao, X., Figueroa-Ramirez, A. C., Tamayo, D., Lee, J. J.-K., Kalocsay, M., Gonzalez-Sanchez, D., Chancay, M. S., McCracken, K. W., Lee, N. N., Ichimura, T., Mori, Y., Valerius, M. T., Wilflingseder, J., Lemos, D. R., Edelman, E. R., & Bonventre, J. V. (2021). Orphan nuclear receptor COUP-TFII enhances myofibroblast glycolysis leading to kidney fibrosis. EMBO Reports, n/a(n/a), e51169. https://doi.org/10.15252/embr.202051169 Cite
