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Pulmonary Cell NewsResearchers reported evidence that the olfactory neuroepithelium was a major site of SARS-CoV2 infection with multiple cell types, including olfactory sensory neurons, support cells, and immune cells, becoming infected.
[Science Translational Medicine]
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Melo, G. D. de, Lazarini, F., Levallois, S., Hautefort, C., Michel, V., Larrous, F., Verillaud, B., Aparicio, C., Wagner, S., Gheusi, G., Kergoat, L., Kornobis, E., Donati, F., Cokelaer, T., Hervochon, R., Madec, Y., Roze, E., Salmon, D., Bourhy, H., … Lledo, P.-M. (2021). COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters. Science Translational Medicine, 13(596). https://doi.org/10.1126/scitranslmed.abf8396 Cite
