Hypoxia and HIF-1 as Key Regulators of Gut Microbiota and Host Interactions

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Scientists discuss recent evidence suggesting that the intricate and multidirectional interactions among the microbiota, hypoxia/hypoxic sensors, and mammalian host cells (intestinal epithelial cells and type-3 innate lymphoid cells) determine how the intestinal barrier and host–microbiota–pathogens connections are molded.
[Trends in Immunology]
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Abstract