Early Invasion of the Bladder Wall by Solitary Bacteria Protects UPEC from Antibiotics and Neutrophil Swarms in an Organoid Model

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Bacteria injected into the organoid lumen entered umbrella-like cells and proliferated to form intracellular bacterial communities -like bodies.
[Cell Reports]
Sharma, K., Thacker, V. V., Dhar, N., Cabrer, M. C., Dubois, A., Signorino-Gelo, F., Mullenders, J., Knott, G. W., Clevers, H., & McKinney, J. D. (2021). Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model. Cell Reports, 36(3). https://doi.org/10.1016/j.celrep.2021.109351 Cite
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