Active Surveillance Characterizes Human Intratumoral T Cell Exhaustion

By
Justin.choi
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Starting with the observation that T cells moved more quickly through mouse tumors as residence time increased and they progressed towards exhaustion, the authors elaborated a non-stimulatory live-biopsy method for real-time study of T cell behaviors within individual patient tumors.
[Journal of Clinical Investigation]
You, R., Artichoker, J., Fries, A., Edwards, A. W., Combes, A. J., Reeder, G. C., Samad, B., & Krummel, M. F. (2021). Active surveillance characterizes human intratumoral T cell exhaustion. The Journal of Clinical Investigation. https://doi.org/10.1172/JCI144353 Cite
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