Core-Shell Hydrogel Microfiber-Expanded Pluripotent Stem Cell-Derived Lung Progenitors Applicable to Lung Reconstruction In Vivo

By
Justin.choi
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The authors established an expansion system of hPSC-derived lung progenitors based on their 3D culture in core-shell hydrogel microfibers, that ensures the maintenance of their bipotency for differentiation into alveolar and airway epithelial cells including alveolar type II cells.
[Biomaterials]
Ikeo, S., Yamamoto, Y., Ikeda, K., Sone, N., Korogi, Y., Tomiyama, L., Matsumoto, H., Hirai, T., Hagiwara, M., & Gotoh, S. (2021). Core-shell hydrogel microfiber-expanded pluripotent stem cell-derived lung progenitors applicable to lung reconstruction in vivo. Biomaterials, 276, 121031. https://doi.org/10.1016/j.biomaterials.2021.121031 Cite
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