Scientists revealed that MK2206 suppressed migration, proliferation, and inflammation in vascular smooth muscle cells. Moreover, MK2206 inhibited proliferation and inflammation of endothelial cells.
[Acta Pharmacologica Sinica]
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Tang, Y., Li, Z., Feng, Y., Yang, H., Hou, C., Geng, C., Yang, P., Zhao, H., & Wang, J. (2021). MK2206 attenuates atherosclerosis by inhibiting lipid accumulation, cell migration, proliferation, and inflammation. Acta Pharmacologica Sinica, 1–11. https://doi.org/10.1038/s41401-021-00729-x Cite