Aromatic Monophenols from Cinnamon Bark Act as Proteasome Inhibitors by Upregulating ER Stress, Suppressing FoxM1 Expression, and Inducing Apoptosis in Prostate Cancer Cells

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Scientists investigated the anticancer potential of abundant monophenols from cinnamon, namely, cinnamaldehyde, cinnamic acid, and eugenol, by hypothesizing that they possess proteasome inhibitory activities capable of suppressing cancer cell proliferation and inducing apoptosis.
[Phytotherapy Research]
Gopalakrishnan, S., & Ismail, A. (n.d.). Aromatic monophenols from cinnamon bark act as proteasome inhibitors by upregulating ER stress, suppressing FoxM1 expression, and inducing apoptosis in prostate cancer cells. Phytotherapy Research, n/a(n/a). https://doi.org/10.1002/ptr.7236 Cite
Abstract