Human iPS-Derived Pre-Epicardial Cells Direct Cardiomyocyte Aggregation Expansion and Organization In Vitro

Researchers showed that differentiating human iPSC-derived lateral plate mesoderm with BMP4, RA and VEGF could generate a premature form of epicardial cells expressing WT1, TBX18, SEMA3D, and SCX within 7 days.