TLR4 Signaling in the Development of Colitis-Associated Cancer and Its Possible Interplay with microRNA-155

Considerable attention has been focused on the regulation of TLR4 signaling in the context of colitis-associated tumorigenesis. MicroRNA-155 and TLR4 exhibited a similar dynamic expression change during colitis-associated cancer (CAC) development and shared similar CAC-promoting properties.