Transcriptional Landscape Associated with Triple Negative Breast Cancer (TNBC) Resistance to Neoadjuvant Chemotherapy Revealed by Single Cell RNA-Seq

Scientists identified the transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy at the single cell level by analyzing publicly-available transcriptome data from more than 5,000 single cells derived from four extinction and four persistence patients, revealing remarkable tumor heterogeneity.