MicroRNA-532-5p Regulates Oxidative Stress and Insulin Secretion Damage in High Glucose-Induced Pancreatic β Cells by Downregulating the Expression Levels of CCND1

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Scientists investigated the specific mechanism underlying the effects of miR‑532‑5p on diabetes. Cell viability was determined using an MTT assay. The expression levels of miR‑532‑5P, cyclin D1, Insulin1 and Insulin2 were detected using reverse transcription‑quantitative PCR.
[Molecular Medicine Reports]
Abstract